Dental & Health Care

The ordinary success rate in egg donation operation varies at 50%. Of course there are aspects that may raise the chance of success. The first to mention is the professionalism of the medical crew. The second to mark is the quality of the donored oocyte. If the donors are young the success possibility increases conciderably. And the final point is the usage of the newest technologies. Just a minority clinics offer all benefits. One of them is AVA-Peter, a Russian infertility clinics in Saint Petersburg. The next describes process they execute. This made them able to reach a 70% success rate in egg cell donation in first half of 2009.

Egg donation involves two persons the first one is called an an egg donor and an egg recipient. The egg donor undergoes IVF process to make her ovaries egg cells. The eggs are afterwards fertilised in the lab by the semen of the egg recipient's husband or partner (or a sperm donor). Theinseminated eggs are called embryos, and one or a pair of them are placed back into the womb of the egg recipient to make a pregnancy.

Differences between IVF and IVF with egg donation

The main difference between 'usual IVF' and 'egg donation IVF' is that another person is needed to aid to form a pregnancy. This is the egg donor, whose eggs are used if the potential mother (the egg recipient) cannot make use of her own eggs to get pregnant. The following is a overall description of all the process stages.

Synchronising the menstrual cycles

Both the egg donor & the egg recipient are to be at the start of their menstrual cycles which is needed to launch egg donation procedures. If you no longer have a steady menstrual cycle, we can have it induced at the right time.This is made by prescribing birth control medicationto both the donor and the recipient along with the agreed time-table. The pills are stopped on the same date by both the donor and the recipient, leading to a menstruation in both women.

The egg donor's treatment

After the egg donor's period starts, she has an ultrasound examination of the uterus and the ovaries to assure the ovaries are inactive and the womb lining is thin. Your egg donor afterwards undertakes medication to stimulate her ovaries to form egg cells. After about 10 days, she takes one more hormone to make the eggs set for harvesting. Egg harvesting is performed by aspirating the eggs from the follicles with a needle incerted into the ovary via the vagina. Her task is now over.

The egg recipient's treatment

Egg recipients may or may not have a normal menstrual cycle. After the period is induced by the pills, you may take one or sometimes two extra injections of a 'down-regulating' drug to guarantee best synchronisation with your donor. In most cases, you will after have a scan to check that the lining of your womb is thin enough and that there are no ulcers right before the start of the treatment cycle. This includes taking oestrogen pillows, cream or patches to build up your uterus lining again. Five days before the planned date for Embryo Transfer, you begin taking progesterone as well as oestrogen.

Inspermation and embryo transfer

The donor eggs harvested are inspermated with the semen of the male partner or a donor. They are developed under control in our laboratory for three or (more frequently) five days. During this time, they go on with dividing and develop. At five days old, embryos are called as| blastocysts. By this stage, our expert embryologists can determine which embryos have the most promising quality. On the date of embryo transfer, a single or a pair of the excellent quality embryos are transferred through the cervical tube into the egg recipient's womb using a thin, soft plastic catheter. This procedure is usually fast and painless.

Following the embryo incertion, you carry on with taking oestrogen and progesterone medication for two weeks and after that take a pregnancy test. If the test shows positive result, you must have a scan to confirm the pregnancy two weeks after. If a 'fetal pole' is visible on the scan, this gives clinical confirmation of your pregnancy.

At AVA-Peter, we reached a 60% success rate in 2008. It was the proven clinical pregnancy rate after insertion of 2 fresh (not frozen) embryos at the 5-day-old blastocyst growth stage. An amount of babies born through egg donation is rising each year as more infertile women know about this form of treatment.

Tags: baby, clinic, Health, pregnancy, Women